Bactericidal activities and biochemical analysis of skin mucus of Cyprinid fish (vol 35, 102731, 2023)

This study reports the bactericidal activity of mucus extracts and biochemical characterization of skin mucus from five Cyprinids, including Labeo rohita, Ctenopharyngodon Idella, Gibelion catla, Hypophthalmichthys molitrix and Cirrhinus mrigala against ten different bacteria extracted from naturally infected fish. The bactericidal activity was measured based on the zone of inhibition (ZOI) and compared against Fosfomycin. Importantly, acidic mucus extracts from five fish species exhibited higher bactericidal activity than organic and aqueous extracts. The acidic skin mucus extracts of C. idella, L. rohita, and G. catla showed higher ZOI against Staphylococcus aureus, Aeromonas hydrophila, and Pseudomonas aeruginosa. The minimum inhibitory concentration (MIC) of acidic mucus extracts from C. Idella, L. rohita, and G. catla was 16 µg/mL against A. hydrophila, P. aeruginosa, and S. aureus.