Reproduction of HLA-A*32:01 and other genetic and ecological factors associated with Vancomycin Drug Reaction With Eosinophilia And Systemic Symptoms in An Electronic Health Record-Based Study

Vancomycin is the most common cause of antibiotic-associated drug reaction with eosinophilia and systemic symptoms (DRESS), and has been strongly associated with HLA-A*32:01, however only 20% carrying this allele develop vancomycin DRESS and other predictive and risk factors are currently unknown.