Targeted delivery of rutin into breast cancer cells via using phenylboronic acid functionalized MgO nanoparticles

Th. Abhishek Singh,Pritam Sadhukhan,Noyel Ghosh,Neelam Thakur,Anirudh Sharma,Neeraj Tejwan,Ashok Pabbathi,Joydeep Das,Parames C. Sil

Materials Science and Engineering: B（2023）

引用 0|浏览3

暂无评分

摘要

•A novel PBA-tagged MgO NPs were synthesized for targeting human breast cancer cells.•The NPs were loaded with Rutin, a natural flavonoid to form MgO-NH-PBA-Rutinnanohybrids.•MgO-NH-PBA-Rutin nanohybrids exhibited pH-dependent drug release property.•MgO-NH-PBA-Rutin nanohybrids showed significant anticancer effect both in vitro and in vivo.•MgO-NH-PBA-Rutin nanohybrids did not exhibit any systemic toxicity.

查看译文

关键词

Breast cancer,Drug delivery,MgO nanoparticles,Rutin,pH-responsive,Reactive oxygen species

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要