HSPA5, as a ferroptosis regulator, may serve as a potential therapeutic for head and neck squamous cell carcinoma

Jia Li,Wenke Xiao,Wei Wei,Miaomiao Wu,Kaixin Xiong,Jinglu Lyu,Yan Li

Molecular Immunology（2023）

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摘要

•HSPA5, as a ferroptosis regulator, may serve as a potential therapeutic for head and neck squamous cell carcinoma.•HSPA5 acts as a potential key-associated regulator of ferroptosis in HNSCC and is highly expressed in HNSCC.•High expression of HSPA5 is associated with migration and prognosis of HNSCC.

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关键词

Head and neck squamous cell carcinoma, (HNSCC), Ferroptosis regulator, HSPA5, Proliferation, Metastasis

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