The functional heterogeneity of PACAP: Stress, learning, and pathology

Abha K. Rajbhandari,Jessica R. Barson,Marieke R. Gilmartin,Sayamwong E. Hammack,Briana K. Chen

Neurobiology of Learning and Memory（2023）

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摘要

•The neuropeptide PACAP regulates many biological and behavioral processes.•Targeting PACAP could innovate treatment for a variety of disorders.•Heterogeneity in PACAP signaling poses challenges for therapeutic development.•Nonetheless, harnessing the PACAP system may be a powerful strategy against disease.

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