ID: 214160 Evoked Muscle and Neural Responses During Spinal Cord Stimulation

Recording evoked compound action potentials (ECAPs) during spinal cord stimulation (SCS) can be used to inform dosing for treatment of chronic pain. Our previous results identified a short latency signal that distorted the appearance of evoked a-beta response at low levels of stimulation, suggesting the activation of a local muscle group creating electromyography (EMG) bleed-through into the spinal cord recordings. In this study, we recorded EMG from the paraspinal muscles of the back and intercostal muscle, along with intercostal nerve recordings during SCS, to confirm this hypothesis.