Tissuegene-c induces long-term analgesic effects through modulation of pain mediators and neuronal sensitization in a monoiodoacetate-induced osteoarthritis pain rat model.

E. Park,J. Seo,Y. Lee, K. Park, K-r. Kim, H. Lee, S. Lee,S. Kim, A. Mobasheri,H. Choi

Osteoarthritis and Cartilage（2023）

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摘要

Our results demonstrated that TG-C exerted potent analgesic effects in a rat MIA model of OA pain by inhibiting the upregulation of pain mediators and modulating neuronal sensitization.

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关键词

osteoarthritis pain rat model,analgesic effects,pain mediators,neuronal sensitization,long-term,monoiodoacetate-induced

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