Neural response to stress differs by sex in young adulthood

Justine E. Cohen,Laura M. Holsen,Maria Ironside,Amelia D. Moser,Jessica M. Duda,Kaylee E. Null,Sarah Perlo,Christine E. Richards,Nara F. Nascimento,Fei Du,Chun Zuo,Madhusmita Misra,Diego A. Pizzagalli,Jill M. Goldstein

Psychiatry Research: Neuroimaging（2023）

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摘要

•Brain activity and connectivity differs in young men and women under stress.•Task performance and affective response during stress did not differ between sexes.•However, under stress, women activated limbic, and in men cognitive control regions.•GABA in prefrontal cortex negatively associated with the brain activity by sex.

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