Multimodal ionic liquid-based chromatographic supports for an effective RNA purification

Rita Carapito,Sandra C. Bernardo,Matheus M. Pereira,Márcia C. Neves,Mara G. Freire,Fani Sousa

Separation and Purification Technology（2023）

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摘要

•Ionic Liquids were immobilized onto silica supports for RNA purification.•The multimodal behaviour of IL-based supports was exploited for RNA binding.•SSi[C3C3NH2Im]Cl support demonstrated selectivity, robustness, and reproducibility.•A greener and more straightforward process for RNA purification is described.

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关键词

Nucleic acids, Ionic liquid, Ionic liquid-based support, Multimodal ligand, Purification

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