Outcome of Moderate-Severe Tricuspid Regurgitation after Pulmonary Endarterectomy or Balloon Pulmonary Angioplasty.

Williams Hinojosa,Alejandro Cruz-Utrilla,Carmen Jimenez Lopez-Guarch,Maite Velazquez-Martin,Teresa Segura de la Cal,Lorena Gomez-Burguento, Macarena Otero,Maria Jesus Lopez-Gude,Rafael Morales,Josemaria Cortina-Romero,Jorge Solis,Fernando Arribas Ynsurriaga,Pilar Escribano-Subias

REVISTA ESPANOLA DE CARDIOLOGIA（2023）

Hosp Univ 12 Octubre

Cited 0|Views23

Abstract

Introduction and objectives: The management of persistent moderate-severe tricuspid regurgitation (TR) in patients with chronic thromboembolic pulmonary hypertension after treatment with pulmonary endarterectomy (PEA) or balloon pulmonary angioplasty (BPA) is not well defined. This study aimed to analyze the progression and predictors of significant persistent postintervention TR and its prognostic impact.Methods: This single-center observational study included 72 patients undergoing PEA and 20 who completed a BPA program with a previous diagnosis of chronic thromboembolic pulmonary hypertension and moderate-to-severe TR.Results: The postintervention prevalence of moderate-to-severe TR was 29%, with no difference between the PEA- or BPA-treated groups (30.6% vs 25% P = .78). Compared with patients with absent-mild postprocedure TR, those with persistent TR had higher mean pulmonary arterial pressure (40.2 +/- 1.9 vs 28.5 +/- 1.3 mmHg P < .001), pulmonary vascular resistance (472 [347-710] vs 282 [196-408] dyn.s/cm(5); P < .001), and right atrial area (23.0 [21-31] vs 16.0 [14.0-20.0] P < .001). The variables independently associated with persistent TR were pulmonary vascular resistance > 400 dyn.s/cm(5) and postprocedure right atrial area > 22 cm(2). No preintervention predictors were identified. The variables associated with increased 3-year mortality were residual TR and mean pulmonary arterial pressure > 30 mmHg.Conclusions: Residual moderate-to-severe TR following PEA-PBA was associated with persistently high afterload and unfavorable postintervention right chamber remodeling. Moderate-to-severe TR and residual pulmonary hypertension were associated with a worse 3-year prognosis.@ 2023 Sociedad Espantola de Cardiologia. Published by Elsevier Espanta, S.L.U. All rights reserved.

Translated text

Key words

Pulmonary hypertension,Tricuspid regurgitation,Balloon angioplasty,Endarterectomy

求助PDF

上传PDF

Bibtex

AI Read Science

AI Summary

AI Summary is the key point extracted automatically understanding the full text of the paper, including the background, methods, results, conclusions, icons and other key content, so that you can get the outline of the paper at a glance.

Example

Background

Key content

Introduction

Methods

Results

Related work

Fund

Key content

Pretraining has recently greatly promoted the development of natural language processing (NLP)
We show that M6 outperforms the baselines in multimodal downstream tasks, and the large M6 with 10 parameters can reach a better performance
We propose a method called M6 that is able to process information of multiple modalities and perform both single-modal and cross-modal understanding and generation
The model is scaled to large model with 10 billion parameters with sophisticated deployment, and the 10 -parameter M6-large is the largest pretrained model in Chinese
Experimental results show that our proposed M6 outperforms the baseline in a number of downstream tasks concerning both single modality and multiple modalities We will continue the pretraining of extremely large models by increasing data to explore the limit of its performance

Upload PDF to Generate Summary

Must-Reading Tree

Example

Generate MRT to find the research sequence of this paper