Associations of CSF PDGFRβ With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic Changes.

Claudia Cicognola,Niklas Mattsson-Carlgren,Danielle van Westen,Henrik Zetterberg,Kaj Blennow,Sebastian Palmqvist,Khazar Ahmadi,Olof Strandberg,Erik Stomrud,Shorena Janelidze,Oskar Hansson

Neurology（2023）

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摘要

In summary, pericyte damage, reflected by CSF PDGFRβ, may be involved in age-related BBB disruption together with neuroinflammation, but is not related to Alzheimer-related pathological changes.

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关键词

csf pdgfrβ,alzheimer disease pathologic changes,aging,blood-brain

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