Intraoperative Awake Language Mapping Correlates to Preoperative Connectomics Imaging: an Instructive Case.
Clinical neurology and neurosurgery(2023)
摘要
Connectomics enables the study of structural-functional relationships in the brain, and machine learning technologies have enabled connectome maps to be developed for individual brain tumor patients. We report our experience using connectomics to plan and guide an awake craniotomy for a tumor impinging on the language area. Preoperative connectomics imaging demonstrated proximity of the tumor to parcellations of the language area. Intraoperative awake language mapping was performed, revealing speech arrest and paraphasic errors at areas of the tumor boundary correlating to functional regions that explained these findings. This instructive case highlights the potential benefits of implementing connectomics into neurosurgical planning.
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关键词
Connectomics,Brain tumor,Speech mapping,Language,Networks
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