SGLT2 Inhibitors and the Risk of Venous Thromboembolism: A Population-based Cohort Study.

Stephanie Aloe, Christopher Filliter,Shahrzad Salmasi, Samuel Igweokpala, Oriana H Y Yu,Vicky Tagalakis,Kristian B Filion

British journal of clinical pharmacology（2023）

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摘要

We found that SGLT2Is were not associated with an increased risk of VTE compared to DPP-4Is. Although we observed a numerically decreased risk of VTE with SGLT2Is, estimates were accompanied by wide 95% CIs. Nonetheless, given the morbidity associated with VTE, our results provide some reassurance regarding the safety of SGLT2Is with respect to VTE.

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