Microarray-Based Detection of Critical Overexpressed Genes in the Progression of Hepatic Fibrosis in Non-Alcoholic Fatty Liver Disease: A Protein-Protein Interaction Network Analysis.

Ali Mahmoudi,Alexandra E Butler,Antonio De Vincentis,Tannaz Jamialahmadi,Amirhossein Sahebkar

Current medicinal chemistry（2023）

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摘要

This PPI network analysis of DEGs identified critical hub genes involved in the progression of fibrosis and the biological pathways through which they exert their effects in NAFLD patients. Those 12 genes offer an excellent opportunity for further focused research to determine potential targets for therapeutic applications.

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关键词

protein–protein interaction network analysis,hepatic fibrosis,critical overexpressed genes,microarray-based,non-alcoholic

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