Clinical Use of an Exposure, Symptom, and Spirometry Algorithm to Stratify Smokers into COPD Risk Phenotypes: A Case Finding Study Combined with Smoking Cessation Counseling.

Our clinical algorithm classified smokers into COPD phenotypes characterized by disease manifestations associated with smoking intensity, significantly increasing the number of smokers to be screened for COPD. Brief smoking cessation counseling, of which smokers were unaware, was well accepted by participants and resulted in a low but clinically meaningful quit rate and could be beneficially incorporated into case finding interventions.