Role of Nox4 in mitigating inflammation and fibrosis in dextran sulfate sodium-induced colitis.

Yura Lee, Sung-Hee Kim,Haengdueng Jeong,Kwang H Kim,Donghun Jeon,Yejin Cho,Daekee Lee,Ki Taek Nam

Cellular and molecular gastroenterology and hepatology（2023）

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摘要

Nox4 protects against injury and plays a crucial role in fibrogenesis in DSS-induced colitis through canonical TGF-β signaling regulation, highlighting a new treatment target.

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关键词

mitigating inflammation,sodium–induced colitis,dextran sulfate sodium–induced,nox4

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