FHOD1 is upregulated in glioma cells and attenuates ferroptosis of glioma cells by targeting HSPB1 signaling.

Fan Zhang,Lixiang Wu,Songshan Feng,Zijin Zhao,Kui Zhang,Abhimanyu Thakur,Zhijie Xu,Qiuju Liang,Yuanhong Liu,Wei Liu,Yuanliang Yan

CNS neuroscience & therapeutics（2023）

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摘要

In summary, this study demonstrated that the FHOD1-HSPB1 axis exerts marked regulatory effects on ferroptosis, and might affect the prognosis and therapeutic response in glioma.

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关键词

ferroptosis, FHOD1, glioma, HSPB1, prognosis

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