Host genetic background regulates the capacity for anti-tumor antibody-dependent phagocytosis.

James E Glassbrook,Justin B Hackett,Maria C Muñiz,Madeline Bross,Greg Dyson,Nasrin Movahhedin, Alexander Ullrich,Heather M Gibson

bioRxiv : the preprint server for biology（2023）

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摘要

Host genetics play a key regulatory role in targeted immunotherapy outcomes, and putative causal genes are identified in murine chromosome 10 which may govern Mφ function during ADCP.

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关键词

anti-tumor,antibody-dependent

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