Exploring the expression and potential function of follicle stimulating hormone receptor in extragonadal cells related to abdominal aortic aneurysm.

V N Tedjawirja, A Mieremet, K B Rombouts, C Yap, A E Neele,B H Northoff,H J Chen,M Vos, D Klaver,K K Yeung, R Balm,V de Waard

PloS one（2023）

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摘要

Despite previous reports, we did not detect FSHR gene expression in various extragonadal cell types, except in occasional female AAA-SMCs. No clear effect on cell activation was observed upon FSH stimulation in any cell type. Our data suggest that a direct effect of FSH in AAA-related extragonadal cells is unlikely to influence AAA.

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关键词

abdominal aortic aneurysm,hormone receptor,extragonadal cells

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