Inactivation of CACNA1H induces cell apoptosis by initiating endoplasmic reticulum stress in glioma.

Sheng Liu,Ying Ba,Chenglong Li,Guangming Xu

Translational neuroscience（2023）

引用 0|浏览0

暂无评分

摘要

Suppression of CACNA1H activated the ERS and thus induced apoptosis in glioma cells. T-type Ca channel inhibitors ABT-639 and NNC55-0396 also induced apoptosis through ERS in glioma cells. Our data highlighted the effect of CACNA1H as an oncogenic gene in human glioma.

查看译文

关键词

T-type Ca2+ channel, glioma, endoplasmic reticulum stress, apoptosis, Cav3.2

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要