A preliminary transcriptomic analysis of the orbitofrontal cortex of antisocial individuals.
CNS neuroscience & therapeutics(2023)
摘要
These preliminary findings suggest that ASPD and CD feature a complex array of functional deficits in the pyramidal neurons and astrocytes of the OFC. In turn, these aberrances may contribute to the reduced OFC connectivity observed in antisocial subjects. Future analyses on larger cohorts are needed to validate these results.
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关键词
antisocial personality disorder, conduct disorder, orbitofrontal cortex, transcriptomics
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