Registration-based biomarkers for neoadjuvant treatment response of pancreatic cancer via longitudinal image registration.

Jon S Heiselman,Brett L Ecker,Liana Langdon-Embry,Eileen M O'Reilly,Michael I Miga,William R Jarnagin,Richard K G Do,Natally Horvat,Alice C Wei,Jayasree Chakraborty

Journal of medical imaging (Bellingham, Wash.)（2023）

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摘要

Volumetric changes measured by longitudinal deformable image registration may yield imaging biomarkers to discriminate neoadjuvant treatment response in ill-defined tumors characteristic of PDAC. Registration-based biomarkers may help to overcome visual limits of radiographic evaluation to improve clinical outcome prediction and inform treatment selection.

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关键词

registration, pancreas, response, survival, biomarker, pancreatic ductal adenocarcinoma

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