Deciphering the single-cell transcriptome network in keloids with intra-lesional injection of triamcinolone acetonide combined with 5-fluorouracil.

Yijun Xia,Youbin Wang,Yan Hao,Mengjie Shan,Hao Liu,Zhengyun Liang, Xinwen Kuang

Frontiers in immunology（2023）

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摘要

Our findings elucidated the molecular and cellular reprogramming of keloids by intra-lesional injection of TAC+5-FU, which will provide new insights to understand the mechanism of action and therapeutic targets.

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关键词

triamcinolone acetonide,5-fluorouracil,keloid,scRNA,transcriptome

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