Combination of Shengmai San and Radix puerariae ameliorates depression-like symptoms in diabetic rats at the nexus of PI3K/BDNF/SYN protein expression.

Ayaz Ahmed,Guirong Zeng,Mudassar Azhar,Fengzhong Wang,Jingru Wang,Bei Fan,Xinmin Liu,Dejiang Jiang,Qiong Wang

Animal models and experimental medicine（2023）

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摘要

This study showed that R-SMS formulation antagonized depressive symptoms in diabetic rats; thus, this formulation might be studied further to develop as an antidepressant.

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关键词

BDNF,depression,Shengmai San,STZ induced diabetes,traditional Chinese medicine

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