FoxA2 is a reliable marker for the diagnosis of yolk sac tumour postpubertal-type.

Costantino Ricci,Francesca Ambrosi,Tania Franceschini,Francesca Giunchi, Giorgia Di Filippo,Eugenia Franchini,Francesco Massari,Veronica Mollica,Valentina Tateo,Federico Mineo Bianchi,Maurizio Colecchia,Andres Martin Acosta,Michelangelo Fiorentino

Histopathology（2023）

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摘要

FoxA2 is a highly sensitive and specific biomarker that supports the diagnosis of YSTpt. FoxA2 is superior to GPC3 and AFP, especially in rare and difficult-to-diagnose histological patterns of YSTpt, but mature glands of Tpt could represent a potential diagnostic pitfall.

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关键词

FoxA2, germ cell tumours of the testis, glypican 3, yolk sac tumour, yolk sac tumour postpubertal-type, alpha-fetoprotein

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