Effect of High-Level PM2.5 on Survival in Lung Cancer: a Multicenter Cohort Study from Hebei Province, China.

Globally, air pollution is the fourth leading risk factor for death, while lung cancer (LC) is the leading cause of cancer-related death. The aim of this study was to explore the prognostic factors of LC and the influence of high fine particulate matter (PM2.5) on LC survival. Data on LC patients were collected from 133 hospitals across 11 cities in Hebei Province from 2010 to 2015, and survival status was followed up until 2019. The personal PM2.5 exposure concentration (μg/m3) was matched according to the patient’s registered address, calculated from a 5-year average for every patient, and stratified into quartiles. The Kaplan–Meier method was used to estimate overall survival (OS), and Cox’s proportional hazard regression model was used to estimate hazard ratios (HRs) with 95