Development of innate immune memory by non-immune cells during Staphylococcus aureus infection depends on reactive oxygen species.

Emmanuel Chaumond, Sandrine Peron,Nathalie Daniel, Yann Le Gouar,Éric Guédon,David L Williams,Yves Le Loir,Gwénaël Jan,Nadia Berkova

Frontiers in immunology（2023）

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摘要

This work improves our understanding of innate immune memory in non-immune cells in the context of infection. In addition to known inducers, probiotics may represent good candidates for the induction of innate immune memory. Our findings may help the development of alternative therapeutic approaches for the prevention of infection.

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关键词

Staphylococcus aureus, Lactococcus lactis, innate immune memory, non-immune cells, epigenetics, immune response, reactive oxygen species

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