Effect of vaccine dosing intervals on Omicron surrogate neutralization after three doses of BNT162b2.

Martin A Prusinkiewicz,Sadaf Sediqi, Ying Jie Li,David M Goldfarb,Michael Asamoah-Boaheng,Nechelle Wall,Pascal M Lavoie,Brian Grunau

Heliyon（2023）

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摘要

Longer intervals between first, second and third doses are independently associated with increased immunogenicity for all tested SARS-CoV-2 strains. Increasing the intervals between the second and third vaccine doses up to 8.9 months provided additive benefits increasing the immunogenicity of BNT162b2 vaccine schedules.

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关键词

Vaccine interval, Immunization, COVID, SARS-CoV-2, Surrogate neutralization

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