Comparison of immunohistochemical mesothelial biomarkers in paired biopsies and effusion cytology cell blocks from pleural mesothelioma.

Mohammed S I Mansour,Adela Huseinzade,Tomas Seidal,Kim Hejny,Athar Maty,Fereshteh Taheri-Eilagh,Ulrich Mager,Annika Dejmek,Katalin Dobra,Hans Brunnström

Cytopathology : official journal of the British Society for Clinical Cytology（2023）

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摘要

Generally, a high concordance for IHC staining was seen between paired biopsies and pleural effusion cell blocks from mesotheliomas, but the somewhat lower agreement for WT1, EMA, and especially MTAP calls for further investigation and local quality assurance. The lower concordance for the sarcomatoid subtype for some markers may indicate biological differences.

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immunohistochemical mesothelial biomarkers,pleural mesothelioma,effusion cytology cell

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