Cervical Cancer in Pregnancy.

FEBRASGO POSITION STATEMENT © 2023. Federação Brasileira de Ginecologia e Obstetrícia. All rights reserved. Key points • The incidence of cancer during pregnancy has increased given women’s tendency to delay pregnancy. Cervical cancer is the third most commonly diagnosed neoplasm during pregnancy. • Screening and diagnosis should be performed as in non-pregnant patients; cervical cytology is an obligatory antenatal exam, and colposcopy with biopsy may be performed at any time of pregnancy. • Pregnancies complicated by the diagnosis of cancer should always be carried out in a reference center by a multidisciplinary team. • The termination of pregnancy for standard treatment in specific situations is supported by law. • Neoadjuvant chemotherapy is a safe alternative treatment during pregnancy to allow reaching fetal maturity. Response rates are high and neoplastic progression during pregnancy is reported in only 2.9% of cases. The risk of fetal malformations from chemotherapy is similar to that of the general population. However, chemotherapy is associated with intrauterine growth restriction, low birth weight, and neonatal myelotoxicity. • In the absence of disease progression, the pregnancy should be carried to term.