Co-administration of rimonabant prevents glucose intolerance in Sprague-Dawley rats treated chronically with lopinavir/ritonavir and zidovudine: an experimental study design.

Brian Lishenga Makamu,Peter Waweru Mwangi,Frederick Okonji Bukachi

The Pan African medical journal（2023）

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摘要

the study results suggest a role for the endogenous cannabinoid system in cART induced metabolic derangements and physical changes. Future studies can directly assay ECS activity in cART associated metabolic syndrome.

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关键词

Antiretroviral therapy, rimonabant, metabolic syndrome, hyperglycemia, endogenous cannabinoids, HIV, protease inhibitors, nucleoside reverse transcriptase inhibitors

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