Bladder cancer mortality trends in Spain: 1980-2021

Objective: We propose to update bladder cancer mortality rates in Spain from 1980 to 2021, by sex and age-group, by autonomous community (AC).Materials and methods: The public online databases of the National Statistical Institute were used to obtain data on population and bladder cancer mortality. Age-standardised mortality rates (ASMRs), all ages and truncated (< 75 and >= 75) were estimated and reported as rates per 100,000 persons. Joinpoint regression software was used for estimation and trend analysis of ASMRs bladder cancer.Results: In the last decade, the ASMR for bladder cancer (all ages, < 75 years and >= 75 years) decreased significantly in Spain for both sexes. This trend was observed in 12 ACs for men and in 4 ACs (Andalusia, Canary Islands, Catalonia and Madrid) for women, although to different degrees. For men, ASMR remained stable in Castilla-Le & oacute;n and La Rioja (< 75 years), Cantabria, Castilla-La Mancha and Valencia (>= 75 years) and the 2 Castilian regions (all ages). For women, ASMR also decreased in Valencia (< 75 and >= 75), Castilla-Le & oacute;n (>= 75), Galicia (>= 75 and all ages) and Navarre (< 75 and all ages).Conclusion: Our results reveal significant variations in trends by AC, sex and age group, emphasizing the need for continued follow-up and targeted interventions to further reduce bladder cancer mortality rates in Spain.