Efficacy and safety of programmed cell death receptor 1 inhibition-based regimens in patients with pediatric malignancies: the real-world study in China.

Ye Hong,Mengjia Song,Yingxia Lan,Juan Wang,Suying Lu,Yu Zhang,Jia Zhu,Feifei Sun,Junting Huang, Juan Liu,Jiaqian Xu,Yanpeng Wu,Haixia Guo,Ruiqing Cai,Zijun Zhen,Yi Que,Yizhuo Zhang

Frontiers in immunology（2023）

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摘要

This largest retrospective analysis demonstrate that PD-1 inhibitor-based regimens are potentially effective and tolerable in pediatric malignancies. Our findings provide references for future clinical trials and practice of PD-1 inhibitors in pediatric cancer patients.

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关键词

pediatric malignancies, PD-1 inhibitors, PD-1 inhibitor-based treatment, safety, efficacy

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