Elevated levels of Interleukin-1β and IL-10 are associated with faster lung function decline in well-treated people with HIV.

Rebekka F Thudium,Nicoline S Arentoft,Hedda Hoel,Shoaib Afzal, Jakob H von Stemann,Julie L Forman, Jon T Wilcke,Thomas Benfield,Marius Trøseid,Álvaro H Borges,Sisse R Ostrowski,Jørgen Vestbo,Ken M Kunisaki,Jens-Ulrik S Jensen,Susanne D Nielsen

The Journal of infectious diseases（2023）

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摘要

Elevated IL-1β and IL-10 were independently associated with faster lung function decline in PWH, suggesting that dysregulated systemic inflammation may play a role in the pathogenesis of chronic lung diseases.

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