The GRAS Salts of Na 2 SiO 3 and EDTA-Na 2 Control Citrus Postharvest Pathogens by Disrupting the Cell Membrane.

Sodium silicate (NaSiO) and ethylenediaminetetraacetic acid disodium salt (EDTA-Na) are inorganic salts classified as 'Generally Recognized as Safe' (GRAS) compounds with great advantages in controlling various pathogens of postharvest fruits and vegetables. Here, we determined the median effective concentration (EC) of NaSiO (0.06%, 0.05%, 0.07% and 0.08%) and EDTA-Na (0.11%, 0.08%, 0.5%, and 0.07%) against common pathogens affecting postharvest citrus fruit, including , , , and . NaSiO and EDTA-Na treatments at the EC decreased the spore germination rate, visibly disrupted the spore cell membrane integrity, and significantly increased the lipid droplets (LDs) of the four postharvest pathogens. Moreover, both treatments at EC significantly reduced the disease incidence of (by 60% and 93.335, respectively) and (by 50% and 76.67%, respectively) relative to the control. Furthermore, NaSiO and EDTA-Na treatment resulted in dramatically lower disease severity of the four pathogens, while also demonstrating no significant change in citrus fruit quality compared with the control. Therefore, NaSiO and EDTA-Na present a promising approach to control the postharvest diseases of citrus fruit.