Examining temporal features of BOLD-based cerebrovascular reactivity in clinical populations.

Kayley-Jasmin Marchena-Romero,Xiang Ji,Rosa Sommer,Andrew Centen,Joel Ramirez, Joshua M Poulin,David Mikulis,Michael Thrippleton,Joanna Wardlaw,Andrew Lim,Sandra E Black,Bradley J MacIntosh

Frontiers in neurology（2023）

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摘要

This study demonstrates that it is feasible to examine individual responses associated with normocapnic and hypercapnic transition periods of a BOLD-based CVR experiment. Studying these features can provide insight on between-subject differences in CVR.

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关键词

cerebrovascular reactivity, inter-regional heterogeneity, non-parametric, sleep apnea, small vessel disease, blood oxygenation level dependent functional magnetic resonance imaging

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