Clinical associations and characteristics of the polyspecific intrathecal immune response in elderly patients with non-multiple sclerosis chronic autoimmune-inflammatory neurological diseases - a retrospective cross-sectional study.

Felix Brauchle,Daniel Rapp,Makbule Senel,André Huss,Jens Dreyhaupt,Veronika Klose,Marie Süße,Klarissa Hanja Stürner,Frank Leypoldt,Hayrettin Tumani,Jan Lewerenz

Frontiers in neurology（2023）

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摘要

In conclusion, PSIIR positivity occurs frequently in non-MS-S patients ≥50 years. Although sometimes apparently coincidental, the PSIIR seems to represent a suitable biomarker for previously unnoticed chronic neurologic autoimmunities, which require further characterization.

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关键词

polyspecific intrathecal immune response,elderly patients,non-multiple,autoimmune-inflammatory,cross-sectional

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