Diet-derived circulating antioxidants and risk of knee osteoarthritis, hip osteoarthritis and rheumatoid arthritis: a two-sample Mendelian randomization study.

Li Huang,Yanqing Xie,Ting Jin,Mengqiao Wang,Zhen Zeng,Lina Zhang,Wenming He,Yifeng Mai, Jianmeng Lu,Han Cen

Frontiers in medicine（2023）

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摘要

Our results demonstrated that genetically determined lifelong higher exposure to absolute circulating levels of retinol is associated with a decreased risk of hip OA. Further MR study with more genetic instruments for absolute circulating levels of antioxidants are needed to confirm our results.

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关键词

circulating antioxidants,knee osteoarthritis,hip osteoarthritis,rheumatoid osteoarthritis,diet-derived,two-sample

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