Kaempferol inhibits SARS-CoV-2 invasion by impairing heptad repeats-mediated viral fusion.

Junwei Gao,Can Cao,Mingfei Shi,Shihao Hong,Shijie Guo,Jing Li,Tengxiao Liang,Ping Song,Ruodan Xu,Ning Li

Phytomedicine : international journal of phytotherapy and phytopharmacology（2023）

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摘要

Kae prevents SARS-CoV-2 infection by blocking membrane fusion and possesses a broad-spectrum anti-fusion ability. These findings provide valuable insights into potential benefits of Kae-containing botanical products as a complementary prophylaxis, especially during the waves of breakthrough infections and re-infections.

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COVID-19,SARS-CoV-2,kaempferol,heptad repeats,fusion,antivirals

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