Lower Urinary Tract Obstruction in Newborns.

Jaime Flores-Torres, Amarilis Sanchez-Valle,Jose R Duncan, Valerie Panzarino, Jessica Marie Rodriguez,Russell S Kirby

Advances in pediatrics（2023）

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摘要

Lower urinary tract obstruction (LUTO) is a rare birth defect with a prevalence between 1 in 5,000 and 1 in 25,000 pregnancies. LUTO is one of the most common causes of congenital abnormalities of the renal tract. Several genetic conditions have been associated with LUTO. Most common causes of LUTO are posterior urethral valves and urethral atresia. Despite available prenatal and postnatal treatments, LUTO is a significant cause of morbidity and mortality in newborns causing significant end stage renal disease and pulmonary hypoplasia.

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关键词

Lower urinary tract obstruction,Posterior urethral valves,Urethral atresia,Prune belly syndrome,Pulmonary hypoplasia,End-stage renal disease

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