Diagnosis, management and genetic analysis of a cat with primary copper hepatopathy.

Recommendations are described for the long-term clinical management of feline PCH - a previously attainable but unreported outcome - with considerations for mitigating the speculated oxidation-exacerbated ocular risks of concurrent URI. This report is the first to include identification of copper aggregates in a liver aspirate from a cat - evidence that liver aspirates from cats could be routinely examined for copper as is standard practice for those from dogs. The cat is also the first reported with PCH and a 'likely pathogenic' heterozygous genotype, which suggests that normal alleles could be recessive to or incompletely/co- dominant with deleterious alleles in cats, as has been reported in other species.