Assessment of the Cardiac Noncoding Transcriptome by Single-Cell RNA Sequencing Identifies FIXER , a Conserved Profibrogenic Long Noncoding RNA.

Parisa Aghagolzadeh,Isabelle Plaisance,Riccardo Bernasconi,Thomas A Treibel,Carlos Pulido Quetglas,Tania Wyss,Leonore Wigger,Mohamed Nemir,Alexandre Sarre,Panagiotis Chouvardas,Rory Johnson,Arantxa González,Thierry Pedrazzini

Circulation（2023）

引用 0|浏览11

暂无评分

摘要

Our results demonstrated that lncRNA expression is sufficient to identify the various cell types composing the mammalian heart. Focusing on cardiac fibroblasts and their derivatives, we identified lncRNAs uniquely expressed in myofibroblasts. In particular, the lncRNA represents a novel therapeutic target for cardiac fibrosis.

查看译文

关键词

cardiac noncoding transcriptome,rna,single-cell

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要