Function of hsa_circ_0006646 as a competing endogenous RNA to promote progression in gastric cancer by regulating the miR-665-HMGB1 axis.

Jing Qin,Shuman Zhen,Jiali Wang,Wei Lv,Yan Zhao,Yuqing Duan,Tianxu Liu, Lei Feng,Guiying Wang,Lihua Liu

Journal of gastrointestinal oncology（2023）

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摘要

For the first time, we demonstrated that axis exerted its tumor-promoting effects in GC, which suggested that could be potentially targeted for GC treatment.

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关键词

Gastric cancer, hsa_circ_0006646, miR-665, high mobility group box 1 ( HMGB1 ), epithelial-, epithelial- mesenchymal transition (EMT)

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