Oxygen-generating nanomaterials for chronic wound management.

NanomedicineAhead of Print EditorialOxygen-generating nanomaterials for chronic wound managementNeha Raina, Parvaiz Ahmad Shiekh, Akhilesh Kumar, Manu Smriti Singh, Piyush Kumar Gupta & Madhu GuptaNeha Raina https://orcid.org/0000-0002-9678-8749School of Pharmaceutical Sciences, Department of Pharmaceutics, Delhi Pharmaceutical Sciences & Research University, Pushp Vihar, Sector 3, MB Road, New Delhi, 110017, IndiaSearch for more papers by this author, Parvaiz Ahmad Shiekh https://orcid.org/0000-0002-2235-0947Centre for Biomedical Engineering, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, 110016, IndiaSearch for more papers by this author, Akhilesh Kumar https://orcid.org/0000-0001-9601-8819Division of Medicine, ICAR-Indian Veterinary Research Institute Izatnagar, Bareilly, 243122, Uttar Pradesh, IndiaSearch for more papers by this author, Manu Smriti Singh https://orcid.org/0000-0003-3068-9884Centre for Life Sciences, Mahindra University, Bahadurpally, Jeedimetla, Hyderabad, 500043, Telangana, IndiaLaboratory of Membrane and Liposome Research, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem 9112102, IsraelSearch for more papers by this author, Piyush Kumar Gupta**Author for correspondence: E-mail Address: dr.piyushkgupta@gmail.comDepartment of Life Sciences, Sharda School of Basic Sciences & Research, Sharda University, Knowledge Park III, Greater Noida, 201310, Uttar Pradesh, IndiaDepartment of Biotechnology, Graphic Era Deemed to be University, Dehradun, 248002, Uttarakhand, IndiaSearch for more papers by this author & Madhu Gupta *Author for correspondence: E-mail Address: madhugupta98@gmail.comhttps://orcid.org/0000-0002-8503-0609School of Pharmaceutical Sciences, Department of Pharmaceutics, Delhi Pharmaceutical Sciences & Research University, Pushp Vihar, Sector 3, MB Road, New Delhi, 110017, IndiaSearch for more papers by this authorPublished Online:13 Jul 2023https://doi.org/10.2217/nnm-2023-0090AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInRedditEmail View articleKeywords: chronic woundshypoxiainflammationnanomaterialsoxygen-releasing materialstherapyReferences1. Sen CK. Human wound and its burden: updated 2020 compendium of estimates. Adv. Wound Care 10(5), 281–292 (2021).Crossref, Google Scholar2. Kang J Il, Park KM, Park KD. Oxygen-generating alginate hydrogels as a bioactive acellular matrix for facilitating wound healing. J. Ind. Eng. Chem. 69, 397–404 (2019).Crossref, CAS, Google Scholar3. Erdem A, Haghniaz R, Ertas YN et al. Methods for fabricating oxygen releasing biomaterials. J. Drug Target. 30(2), 188–199 (2022).Crossref, Medline, CAS, Google Scholar4. Shiekh PA, Singh A, Kumar A. Exosome laden oxygen releasing antioxidant and antibacterial cryogel wound dressing OxOBand alleviate diabetic and infectious wound healing. Biomaterials 249, 120020 (2020).Crossref, Medline, CAS, Google Scholar5. Ashammakhi N, Darabi MA, Kehr NS et al. Advances in controlled oxygen generating biomaterials for tissue engineering and regenerative therapy. Biomacromolecules 21(1), 56–72 (2020).Crossref, Medline, CAS, Google Scholar6. Zehra M, Zubairi W, Hasan A et al. Oxygen generating polymeric nano fibers that stimulate angiogenesis and show efficient wound healing in a diabetic wound model. Int. J. Nanomed. 15, 3511–3522 (2020).Crossref, Medline, CAS, Google Scholar7. Tu C, Lu H, Zhou T et al. Promoting the healing of infected diabetic wound by an anti-bacterial and nano-enzyme-containing hydrogel with inflammation-suppressing, ROS-scavenging, oxygen and nitric oxide-generating properties. Biomaterials 286, 121597 (2022).Crossref, Medline, CAS, Google Scholar8. Liu L, Wang C, Li Y et al. Manganese dioxide nanozyme for reactive oxygen therapy of bacterial infection and wound healing. Biomater. Sci. 9(17), 5965–5976 (2021).Crossref, Medline, CAS, Google Scholar9. Hadanny A, Zubari T, Tamir-Adler L et al. Hyperbaric oxygen therapy effects on pulmonary functions: a prospective cohort study. BMC Pulm. Med. 19(1), 148 (2019).Crossref, Medline, Google Scholar10. Lee Y-H, Lin S-J. Chitosan/PVA hetero-composite hydrogel containing antimicrobials, perfluorocarbon nanoemulsions, and growth factor-loaded nanoparticles as a multifunctional dressing for diabetic wound healing: synthesis, characterization, and in vitro/in vivo evaluation. Pharmaceutics 14(3), 537 (2022).Crossref, Medline, Google Scholar11. Aghajanpour S, Esfandyari-Manesh M, Ghahri T et al. Impact of oxygen-calcium-generating and bone morphogenetic protein-2 nanoparticles on survival and differentiation of bone marrow-derived mesenchymal stem cells in the 3D bio-printed scaffold. Colloids Surf. B. Biointerfaces 216, 112581 (2022).Crossref, Medline, CAS, Google Scholar12. Yang Z, Chen H, Yang P et al. Nano-oxygenated hydrogels for locally and permeably hypoxia relieving to heal chronic wounds. Biomaterials 282, 121401 (2022).Crossref, Medline, CAS, Google Scholar13. Wang Q, Qiu W, Li M et al. Multifunctional hydrogel platform for biofilm scavenging and O2 generating with photothermal effect on diabetic chronic wound healing. J. Colloid Interface Sci. 617, 542–556 (2022).Crossref, Medline, CAS, Google ScholarFiguresReferencesRelatedDetails Ahead of Print STAY CONNECTED Metrics Downloaded 0 times History Received 27 March 2023 Accepted 7 June 2023 Published online 13 July 2023 Information© 2023 Future Medicine LtdKeywordschronic woundshypoxiainflammationnanomaterialsoxygen-releasing materialstherapyFinancial & competing interests disclosureThe authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.No writing assistance was utilized in the production of this manuscript.PDF download