Single-cell RNA-sequencing identifies various proportions of excitatory and inhibitory neurons in cultured human fetal brain cortical tissues.

Rong Liu,Wei Dong,Dan Xiong, Lanqi Hu, Haoran Zhang, Xiaoping Yuan,Zhonghui Tang,Fang Fu,Xin Yang,Xia Wu

Frontiers in neuroscience(2023)

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摘要
This study presents a novel strategy to obtain excitatory and inhibitory neuronal cells from the culture of fetal cortical tissues. The findings shed light on the mechanisms underlying neurogenesis and provide an approach that might contribute to future research investigating the pathophysiology of various neural disorders.
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cultured human fetal brain,neurons,cortical tissues,single-cell,rna-sequencing
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