Type IV pili facilitated natural competence in Fusobacterium nucleatum

Blake E. Sanders,Ariana Umaña,Tam T.D. Nguyen,Kevin J. Williams,Christopher C. Yoo,Michael A. Casasanta,Bryce Wozniak,Daniel J. Slade

Anaerobe（2023）

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摘要

•The first report of natural competence in the ‘oncomicrobe’ Fusobacterium nucleatum.•Bioinformatic analysis showing natural competence is conserved in Fusobacterium.•Validation of Type IV pili facilitated natural competence.•Fusobacterium native DNA Methylation is critical to facilitate natural competence.

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关键词

Fusobacterium,Fusobacterium nucleatum,DNA methyltransferase,Natural competence,Type IV pili,Transformation,Bacterial genetics

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