Bladder detrusor muscular ring size on magnetic resonance imaging is associated with moderate and severe american urological association symptom index scores in untreated men with benign prostatic hyperplasia- a potential novel predictor of lower urinary tract symptoms

You have accessJournal of UrologyCME1 Apr 2023MP24-03 BLADDER DETRUSOR MUSCULAR RING SIZE ON MAGNETIC RESONANCE IMAGING IS ASSOCIATED WITH MODERATE AND SEVERE AMERICAN UROLOGICAL ASSOCIATION SYMPTOM INDEX SCORES IN UNTREATED MEN WITH BENIGN PROSTATIC HYPERPLASIA- A POTENTIAL NOVEL PREDICTOR OF LOWER URINARY TRACT SYMPTOMS Kiran Nandalur, David Walker, Hong Ye, Sayf Al-Katib, Brian Seifman, David Gangwish, Abhay Dhaliwal, Ervin Connor, Kayla Dobies, Channing Sesoko, Wesley Dejoie, Bernadette Zwaans, Sirisha Nandalur, Jennifer Nyguyen, and Jason Hafron Kiran NandalurKiran Nandalur More articles by this author , David WalkerDavid Walker More articles by this author , Hong YeHong Ye More articles by this author , Sayf Al-KatibSayf Al-Katib More articles by this author , Brian SeifmanBrian Seifman More articles by this author , David GangwishDavid Gangwish More articles by this author , Abhay DhaliwalAbhay Dhaliwal More articles by this author , Ervin ConnorErvin Connor More articles by this author , Kayla DobiesKayla Dobies More articles by this author , Channing SesokoChanning Sesoko More articles by this author , Wesley DejoieWesley Dejoie More articles by this author , Bernadette ZwaansBernadette Zwaans More articles by this author , Sirisha NandalurSirisha Nandalur More articles by this author , Jennifer NyguyenJennifer Nyguyen More articles by this author , and Jason HafronJason Hafron More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003249.03AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The etiology of lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) remains uncertain. The purpose of our study was to quantitatively analyze anatomic characteristics on magnetic resonance imaging (MRI) to assess novel independent factors for LUTS. METHODS: This retrospective single-institution study evaluated treatment-naïve men who underwent prostate MRI within 3 months of American Urological Association Symptom Index (AUASI) scoring from June 2021 to September 2022. Factors measured on MRI included: size of the detrusor muscular ring (DMR) surrounding the bladder outlet, prostate volume, intravesicular prostate protrusion (IPP) volume, and prostate urethra angle (PUA). Multivariable logistic regression and ROC analysis were used to analyze factors for moderate/severe (AUASI≥8) and severe LUTS (AUASI≥20). RESULTS: 318 total men (mean age: 66.2 (SD:8.0)) were included: 31 with severe symptoms, 131 with moderate symptoms, and 156 with mild symptoms. Increasing age (p=0.02;OR:1.05(1.01-1.08)), PUA (p=0.02;OR:1.05(1.01-1.09), and DMR size measured as diameter (p<0.001;OR:5.6(3.37-9.16)) were significantly independently associated with AUASI≥8. For every one cm increase in DMR diameter, patients had approximately five times the odds for AUASI≥8. Increasing DMR size (diameter p<0.001;OR: 2.74 (1.76-4.27) was independently associated with severe symptoms. CONCLUSIONS: Expansion of the detrusor muscular ring surrounding the bladder outlet is a novel anatomic factor independently associated with moderate/severe LUTS. Prostate volume and IPP volume were unrelated to AUASI scoring. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e317 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Kiran Nandalur More articles by this author David Walker More articles by this author Hong Ye More articles by this author Sayf Al-Katib More articles by this author Brian Seifman More articles by this author David Gangwish More articles by this author Abhay Dhaliwal More articles by this author Ervin Connor More articles by this author Kayla Dobies More articles by this author Channing Sesoko More articles by this author Wesley Dejoie More articles by this author Bernadette Zwaans More articles by this author Sirisha Nandalur More articles by this author Jennifer Nyguyen More articles by this author Jason Hafron More articles by this author Expand All Advertisement PDF downloadLoading ...