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加强非结核分枝杆菌病治疗药物研究

Chinese Journal of Clinical Infectious Diseases(2023)

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Abstract
全球非结核分枝杆菌(Nontuberculous mycobacteria,NTM)感染和疾病均呈增长趋势。非结核分枝杆菌病(Nontuberculous mycobacterial disease,NTMD)是一种全球健康负担逐渐加重的公共卫生问题,发病率、病死率和经济成本逐渐升高。抗菌药物是治疗NTMD的基石,但NTM对许多抗菌药物具有固有耐药性,治疗较为棘手,尤其免疫功能低下和伴基础疾病和慢性肺病患者,即使采取多种药物联合的长程治疗,NTMD治疗的临床成功率<50%,急需抗NTM新药。本文对NTMD治疗药物新进展进行阐述。
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Key words
Nontuberculous mycobacteria,Medication,Research progress
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