CO63 Comparative Clinical Effectiveness of Monoclonal Antibodies for the Treatment of Relapsing Multiple Sclerosis: A Systematic Review and Network Meta-Analysis

D. Nikitin, G. Lin, A. McKenna, S. Herron-Smith, J. Campbell, F.O. Agboola

Value in Health（2023）

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摘要

To evaluate the relative clinical effectiveness of five monoclonal antibodies (natalizumab, ofatumumab, ocrelizumab, rituximab, ublituximab) as first-line disease-modifying therapies (DMT) for relapsing forms of multiple sclerosis (MS); and to compare these treatments to placebo and oral DMTs (dimethyl fumarate, fingolimod, ozanimod, ponesimod, and teriflunomide).

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关键词

multiple sclerosis,monoclonal antibodies,systematic review,meta-analysis

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