Relation of FVIII activity levels with global assays of hemostasis in persons with hemophilia A

Introduction Global assays of hemostasis provide a more detailed view of thrombin generation and clot formation and may be helpful in identifying persons with hemophilia at a higher risk of bleeding. Here, we investigated the continuous relation between factor VIII (FVIII) activity as measured in routine clinical care and parameters of two global assays of hemostasis.